Chinese Doctors Directory Chinese Medical School Graduates Gathering in North America

Additional Information

Certification: Board Certified in Pathology Anatomical Pathology and Clinical Pathology, Gastrointestinal/Liver Pathology

Appointment:Chair of the Department of Pathology

Hospital Affiliations:Northwestern Memorial Hospital

Ph.D.: China Medical University, Molecular Pathology (1992)

Research Interests: The long-term objective of our research is to study molecular mechanism and
chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking
model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary
iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis;
2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3)
to develop an efficient strategy on the prevention of chronic inflammation-driven
carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on
colorectal,pancreatic, and liver carcinogenesis.